Tissue Regeneration Therapy (TRT)

“Regenerating and rebuilding damaged joints with your own immune system”

The Foot and Ankle Clinic continues to embrace the latest treatment therapies available and are now proud to offer the latest clinical advancements in Tissue Regeneration Therapy (TRT) using varieties of alternate, safe and clinically proven injection therapies. In particular, our Sale clinic based Musculoskeletal and Sports Podiatrist, Dr. James Ferrie, has done extensive research and training to provide him with the necessary skills for providing these unique therapies as well as the expertise and knowledge to diagnose and treat Musculoskeletal injuries of the lower limb.

Dr. Ferrie offers a range of three specific and safe treatment options that don’t involve any synthetic or harmful chemicals: PROLOTHERAPY, PLATELET-RICH PLASMA (PRP) and ORTHOKINE THERAPY.

The clinical applications and indications for each of these treatments vary and are case dependent as are the costs involved. Once you have been thoroughly assessed and diagnosed (including diagnostic imaging such as x-rays or ultrasound) your Podiatrist will provide detailed information and advice regarding the therapy that best suits your condition.

Dr. James Ferrie Your Tissue Regeneration Therapy Expert

About Dr James Ferrie

Dr. Ferrie is The Foot and Ankle Clinic’s Musculoskeletal Podiatrist. Having completed four years bachelor of Podiatry from LaTrobe University in 2011, he developed a strong interest in Musculoskeletal medicine and the innovative way to assessing and treating chronic conditions Musculoskeletal conditions. He has undertaken post-graduate training in blood collection, Platelet-rich plasma, Orthokine, Prolotherapy, Dry needling, Laser therapy and surgery, ECSWT, clinical diagnostic ultrasound and guided injection. He has also trained at the world leading Interventional Orthopedics Foundation in Colorado USA. James is also a teacher of diagnostic ultrasound.

tissue regeneration therapy

What Conditions can Tissue Regenerative Therapy be used for?

  • arthritis
  • tendon pain
  • tendon and ligament tears
  • Nerve pain/entrapments
  • chronic pain
  • unstable joints
  • post surgery pain
  • slow healing injuries
  • Chronic wounds

Running man - Tissue Regeneration Therapy (TRT)


What can I expect at my 1st consultation ?

  • Listen to you
  • Accurate diagnosis from previous scans and on-site ultrasound assessment.
  • Physical assessment/biomechanical assessment.
  • Develop a tailor-made comprehensive treatment plan to manage your condition.
  • Discussing your suitability for a regenerative tissue therapy.

Does it hurt?

We do not believe treatments should be painful. Before your injections, it is common for a nerve block to be performed ensuring a pain-free procedure.

What is the success rates of tissue regenerative treatments?

Success rates are high. 80% of patients receive significant relief after treatment. Success will vary depending on the severity of the condition and general health & age. There are some patients who, due to certain health conditions or medical history, will not be suitable for regenerative injections.

What are the risks?

Tissue regenerative procedures have a proven track record when it comes to safety; complications are very uncommon mainly as these procedures utilise your own cells and very fine needles.

There are some inherent risks which are present for any injection, and these include infection and injury to nerve or blood vessel. At The Foot and Ankle Clinic, we use the latest in clinical ultrasound guidance to ensure best practice, and all laboratory work is conducted in a sterile air environment to provide the highest safety standards.

On-site Musculoskeletal ultrasound

At The Foot and Ankle Clinic’s Sale Practice, Dr. James Ferrie utilises advanced ultrasound imaging onsite, allowing for a comprehensive treatment plan to be established at your initial consultation.

Clinical evidence and research support ultrasound as the first diagnostic test for numerous Musculoskeletal (MSK) conditions. Diagnostic ultrasound offers many important advantages compared to computed tomography (CT) and magnetic resonance imaging (MRI), in terms of safety and effectiveness. Diagnostic ultrasound is noninvasive and offers real-time imaging, allowing for examinations of structures at rest and in motion. This ability to capture the movement of Musculoskeletal components differentiates it from other imaging modalities and can permit more accurate diagnoses.

What are the benefits of onsite ultrasound?

Ultrasound allows for accuracy and safety when performing procedures such a nerve blocks, soft tissue and joint injection. Fast, accurate on-site diagnostic imaging reduces unnecessary therapies and allows for timely treatment of your condition without delay.

Ultrasound-guided injections

Ultrasound allows for visualising of musculoskeletal tissue. We can identify the injured tissue in the office without having to wait for an MRI. During treatment, we inject the injured structures and maintain continued needle visualisation of the targeted areas.

On-site Laboratory for Platelet-Rich Plasma Treatment

In most clinics around the world that do Platelet-Rich Plasma treatments, the process of creating the Platelet-Rich Plasma involves extracting a patient’s own blood and running it through a simple automated bedside centrifuge machine to separate the plasma and concentrate the blood platelets, which are then automatically extracted and used for the injection and in some case the blood is not enriched.

These machines are not very good at removing the undesirable cells from the resulting mixture. Our Platelet-Rich Plasma has greater purity, is concentrated and customisable since it is created in a lab environment by a skilled clinician who separates and concentrates all of the blood’s desirable components and removes the undesirable cells.

The laboratory we have onsite also allows for additional blood to be stored in our medical grade freezer. This is so it can be used for future treatments. Our medical grade freezers are temperature controlled and monitored by the latest technology ensuring safety and best practices.

Nick Riewoldt Orthokine

St Kilda Captain Nick Riewoldt Credits Orthokine Therapy on Injured Knee




Kobe Bryant Orthokine

Kobe Bryant in Germany for Annual Knee Treatment




At the Foot and Ankle Clinic our highly qualified team of Podiatrists are all members of the Australian Podiatry Association and offer a combined 50 years’ experience.

Put your feet in our hands! See Dr. Ferrie today at our Sale clinic.