Prolotherapy, also referred to as Sclerosing Injections, is an injection-based therapy for chronic Musculoskeletal pain which has been used for over 60 years. Prolotherapy works by promoting your body’s natural repair mechanisms to heal injured or weakened joints, ligaments and tendons. (Ligaments are the tough tissues which connect bones to one another, while tendons are a similar type of tissue connecting muscles to bones). It is a natural, non-surgical method of stimulating growth when ligaments or tendons have been stretched/damaged or torn.

Prolotherapy treatment to a knee

What is involved?

Prolotherapy involves injecting a solution such as dextrose (glucose sugar water) into painful ligament and tendon sites, and/or into adjacent joints. The solution is safe and water-soluble, which is easily excreted from the body after having the initial desired effect. It works by causing cells to lose water, which leads to a localised inflammatory reaction, stimulating the growth of collagen fibers and connective tissue. This process is thought to thicken, tighten and strengthen the weak tissue, resulting in a stronger tendon or ligament that can hold body structures in place more effectively.

An alternative to Cortisone Injections

As the injured area heals, pain is usually reduced or eliminated. This biological process can often take up to six to eight weeks, which explains why you may not feel benefits immediately. A series of injections are usually given 4 weeks apart to encourage optimal tissue growth. A local anesthetic is used to ensure minimal discomfort with the injections. Prolotherapy is often used as an alternative to cortisone injections, which can often weaken connective tissue with long-term consequences.

On-site Musculoskeletal ultrasound

At The Foot and Ankle Clinic’s Sale Practice, Dr. James Ferrie utilises advanced ultrasound imaging onsite, allowing for a comprehensive treatment plan to be established at your initial consultation.



What can I expect at my 1st consultation ?

  • Listen to you
  • Accurate diagnosis from previous scans and on-site ultrasound assessment.
  • Physical assessment/biomechanical assessment.
  • Develop a tailor-made comprehensive treatment plan to manage your condition.
  • Discussing your suitability for a regenerative tissue therapy.

Does it hurt?

We do not believe treatments should be painful. Before your injections, it is common for a nerve block to be performed ensuring a pain-free procedure.

What is the success rates of tissue regenerative treatments?

Success rates are high. 80% of patients receive significant relief after treatment. Success will vary depending on the severity of the condition and general health & age. There are some patients who, due to certain health conditions or medical history, will not be suitable for regenerative injections.

What are the risks?

Tissue regenerative procedures have a proven track record when it comes to safety; complications are very uncommon mainly as these procedures utilise your own cells and very fine needles.

There are some inherent risks which are present for any injection, and these include infection and injury to nerve or blood vessel. At The Foot and Ankle Clinic, we use the latest in clinical ultrasound guidance to ensure best practice, and all laboratory work is conducted in a sterile air environment to provide the highest safety standards.

At the Foot and Ankle Clinic our highly qualified team of Podiatrists are all members of the Australian Podiatry Association and offer a combined 50 years’ experience.

Put your feet in our hands! See Dr. Ferrie today at our Sale clinic.